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Curr Biol. 1998 Jun 4;8(12):R422-4.

Transcription: gene control by targeted histone acetylation.

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1
Laboratory of Molecular Embryology, NICHD, NIH, Bethesda, Maryland 20892-5431, USA. awlme@helix.nih.gov

Abstract

A transcriptional regulator in yeast, Gcn5p, activates transcription by targeted acetylation of specific lysine residues in the amino-terminal tails of histones. This targeted modification is restricted to nucleosomes assembled on the promoters of Gcn5p-responsive genes.

PMID:
9637914
[Indexed for MEDLINE]
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