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Hum Pathol. 1998 Jun;29(6):649-51.

Cat-scratch disease simulating Histiocytosis X.

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Department of Pathology, Gunderson Clinic, Ltd, LaCrosse, WI 45601, USA.


Cat-scratch disease is a self-limited condition commonly causing a benign chronic lymphadenopathy in children. Osteolytic lesions are a rare complication, but have been previously reported. We report a case of a solitary osteolytic lesion of the skull whose clinical, radiographic and pathological features were initially interpreted as being consistent with Histiocytosis X. Subsequently, positive serological titers for Bartonella, a history of a cat-scratch antecedent to the onset of clinical symptoms and review of the original histopathology confirmed the diagnosis of cat-scratch disease. We reviewed the English language literature on osteolytic lesions associated with cat-scratch disease and compare the current case with those previously reported.

[Indexed for MEDLINE]

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