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Curr Biol. 1998 May 21;8(11):R368-72.

Nucleocytoplasmic transport: driving and directing transport.

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1
Department of Biochemistry, Dartmouth Medical School, Hanover, New Hampshire 03755, USA. charles.cole@dartmouth.edu

Abstract

Nucleocytoplasmic transport involves assembly and movement across the nuclear envelope of cargo-receptor complexes that interact with the small GTPase Ran. The asymmetric distribution of Ran regulator proteins, RanGAP1 and RCC1, provides the driving force and directionality for nuclear transport.

PMID:
9635180
[Indexed for MEDLINE]
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