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South Med J. 1998 Jun;91(6):527-32.

Dynamic magnetic resonance imaging in evaluating suspicious breast lesions: correlation with pathologic findings.

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1
Department of Radiology, University of South Alabama, Mobile 36617, USA.

Abstract

BACKGROUND:

We used dynamic magnetic resonance imaging (MRI) to study breast lesions in 13 women.

METHODS:

We observed differences in contrast uptake between benignancy and malignancy in 14 suspicious breast lesions. Three-dimensional (3D) gradient echo sequences were obtained before and after administration of gadolinium-based contrast medium (0.16 mmol/kg). The percentage of signal increase in lesions was measured in a series of five 90-second sequences, and time-enhancement patterns were correlated with pathologic diagnoses.

RESULTS:

Seven benign lesions and three breast cancer recurrences showed less than 185% signal increase at 90 seconds after contrast administration. Three new breast cancers and one recently biopsied benign lesion showed more than 185% signal increase at 90 seconds.

CONCLUSION:

Using this MRI technique, we can discriminate between new breast cancers (more than 185% early signal increase) and breast cancer recurrence and/or benign lesions (less than 185% early signal increase) but cannot distinguish recurrent from benign lesions.

[Indexed for MEDLINE]

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