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Neurology. 1998 Jun;50(6):1857-9.

Hemopericardium and cardiac tamponade after thrombolysis for acute ischemic stroke.

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University of Pennsylvania Medical Center, Philadelphia, USA.


Hemorrhage is the major complication of IV recombinant tissue plasminogen activator (rt-PA) treatment for stroke. We report three patients with mild or indistinct cardiac symptoms prior to thrombolysis in whom hemodynamically significant cardiac tamponade occurred after treatment with rt-PA. Acute ischemic stroke patients may have undetected myocardial or pericardial disease that may pose a risk for hemopericardium and life-threatening tamponade after treatment with rt-PA.

[Indexed for MEDLINE]

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