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Eur J Clin Microbiol Infect Dis. 1998 Feb;17(2):117-9.

Detection of human herpesviruses 6 and 7 in heart transplant recipients by a multiplex polymerase chain reaction method.

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Dipartimento di Biologia Molecolare, Università di Siena, Italy.


In order to evaluate the possible reactivation of human herpesviruses 6 (HHV-6) and 7 (HHV-7) after heart transplantation, buffy-coat and plasma specimens from 21 transplant patients and 56 healthy blood donors were examined for HHV-6 and HHV-7 DNA by polymerase chain reaction. Human herpesvirus 6 and HHV-7 infection or reactivation has been suggested to play a role in cytomegalovirus disease progression in renal transplant recipients. In the present study, however, no significant difference in the prevalence of HHV-6 and HHV-7 was found between the immunosuppressed and the healthy population; moreover, no viral reactivation was found in the heart transplant recipients.

[Indexed for MEDLINE]

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