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J Pediatr. 1998 Jun;132(6):1061-3.

Lidocaine iontophoresis for topical anesthesia before intravenous line placement in children.

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  • 1Department of Pediatrics, Egleston Children's Hospital, Emory University School of Medicine, Atlanta, Georgia, USA.


In a double-blind randomized trial including 42 children aged 7 to 18 years, less pain occurred with intravenous placement after iontophoresis of 2% lidocaine with epinephrine, as reported by patients (p = 0.005), parents (p = 0.001), intravenous personnel (p = 0.009), and investigators (p = 0.0002) compared with placebo therapy. Lidocaine iontophoresis provides rapid and effective topical anesthesia for intravenous access in children.

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