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Seizure. 1998 Apr;7(2):167-71.

Hypothalamic hamartomas causing gelastic epilepsy: two cases and a review of the literature.

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Department of Neurosurgery, Newcastle General Hospital, UK.


Two cases of hypothalamic hamartomas causing gelastic epilepsy are described. The clinical presentations and the radiological features are presented, and the mechanisms involved in laughing attacks are discussed. The literature is reviewed and it is suggested the complete extirpation of the hamartomas is the treatment of choice in gelastic epilepsy.

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