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Emerg Infect Dis. 1998 Apr-Jun;4(2):317-20.

Molecular fingerprinting of multidrug-resistant Salmonella enterica serotype Typhi.

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1
Central Public Health Laboratory, London, United Kingdom.

Abstract

For epidemiologic investigations, the primary subdivision of Salmonella Typhi is vi-phage typing; 106 Vi-phage types are defined. For multidrug-resistant strains the most common types have been M1 (Pakistan) and E1 (India, Pakistan, Bangladesh, and the Arabian Gulf); a strain untypable with the Vi phages has been responsible for a major epidemic in Tajikistan. Most often, isolates from the Indian subcontinent have been resistant to ampicillin, chloramphenicol, streptomycin, sulfonamides, tetracyclines, and trimethoprim; but in the 1997 Tajikistan outbreak, the epidemic strain was also resistant to ciprofloxacin. For multidrug-resistant strains, subdivision within phage type can be achieved by plasmid profile typing and pulsed-field gel electrophoresis.

PMID:
9621206
PMCID:
PMC2640144
DOI:
10.3201/eid0402.980223
[Indexed for MEDLINE]
Free PMC Article
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