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Emerg Infect Dis. 1998 Apr-Jun;4(2):251-61.

Enteroaggregative Escherichia coli.

Author information

1
University of Maryland School of Medicine, Baltimore 21201, USA. jnataro@umppa1.ab.umd.edu

Abstract

Enteroaggregative Escherichia coli (EAEC), an increasingly recognized cause of diarrhea in children in developing countries, has been particularly associated with persistent diarrhea (more than 14 days), a major cause of illness and death. Recent outbreaks implicate EAEC as a cause of foodborne illness in industrialized countries. The pathogenesis of EAEC infection is not well understood, but a model can be proposed in which EAEC adhere to the intestinal mucosa and elaborate enterotoxins and cytotoxins, which result in secretory diarrhea and mucosal damage. EAEC's ability to stimulate the release of inflammatory mediators may also play a role in intestinal illness.

PMID:
9621195
PMCID:
PMC2640136
DOI:
10.3201/eid0402.980212
[Indexed for MEDLINE]
Free PMC Article

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