Format

Send to

Choose Destination
Int J Food Microbiol. 1998 Apr 14;40(3):177-83.

Antimicrobial spectrum and target site of D-3-phenyllactic acid.

Author information

1
Laboratoire de Microbiologie Alimentaire, Institut de Recherche en Biologie Appliquée, Université de Caen, France.

Abstract

Geotrichum candidum excretes D-3-phenyllactic acid, which inhibits the growth of Listeria monocytogenes. It was found to inhibit a range of gram-positive bacteria found in humans and foodstuffs, such as Staphylococcus aureus and Enterococcus faecalis, and gram-negative bacteria from humans, such as Providencia stuartii and Klebsiella oxytoca. Scanning electron microscope studies on the effect of D-3-phenyllactic acid on L. monocytogenes showed that it caused changes in bacterial behavior and structure. The bacteria formed aggregates and secreted polysaccharides; their cell walls lost their rigidity, causing the cells to swell. Finally the bacteria broke down completely and the cells disintegrate.

PMID:
9620125
DOI:
10.1016/s0168-1605(98)00031-2
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center