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Trends Microbiol. 1998 May;6(5):203-8.

Bacterial production of carbapenems and clavams: evolution of beta-lactam antibiotic pathways.

Author information

1
Dept of Biochemistry, University of Cambridge, UK.

Abstract

Research into two of the four classes of naturally produced beta-lactams--the clavams and carbapenems--has started to throw light upon their biochemical pathways and underlying genetics. Interesting similarities between these two classes, from their joint discovery to an apparently common beta-lactam ring-forming enzyme, are now being revealed.

PMID:
9614345
DOI:
10.1016/s0966-842x(98)01251-7
[Indexed for MEDLINE]

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