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Trends Biochem Sci. 1998 May;23(5):185-9.

Importins and exportins: how to get in and out of the nucleus.

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Dept of Biochemistry and Biophysics, UCSF 94143-0448, USA.

Erratum in

  • Trends Biochem Sci 1998 Jul;23(7):235.


Every minute, several million protein and RNA molecules must be transported between the cytoplasm and the nucleus of a eukaryotic cell. The characterization of mediators, receptors and accessory factors for different nuclear import and export pathways has provided a glimpse at the molecular machinery that is responsible for these trafficking events. It appears that both inbound and outbound traffic is mediated by a protein family of related transport factors that can be classified as importins and exportins.

[Indexed for MEDLINE]

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