Seizures are generally regarded as a manifestation of extreme, generally near-fatal carbon monoxide poisoning. A case is described in which a seizure attributable to carbon monoxide poisoning occurred in a small child at a level not thought to be associated with serious neurologic toxicity. A literature review of the occurrence of seizures in carbon monoxide poisoning found that no particular degree of carboxyhemoglobin was correlated with the presence of seizures. A seizure with no other apparent cause occurring in circumstances in which carbon monoxide toxicity would be suspected can be attributed to carbon monoxide poisoning.