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Cytogenet Cell Genet. 1997;79(3-4):198-200.

The two human organic cation transporter genes SLC22A1 and SLC22A2 are located on chromosome 6q26.

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1
Department of Human Genetics, University of W├╝rzburg, Biozentrum, Germany.

Abstract

Polyspecific transporters for organic cations (OCT) belong to a new protein family which also include organic anion transporters. The first human transporters from this family (OCT1, OCT2) have been recently cloned. They translocate small cations like tetraethylammonium, choline and monoamine neurotransmitters and are involved in hepatic and renal cation excretion, respectively. We have localized the OCT1 and OCT2 genes (SLC22A1, SLC22A2) on chromosome 6q26.

PMID:
9605850
[Indexed for MEDLINE]
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