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Curr Opin Immunol. 1998 Apr;10(2):220-5.

B-cell receptor regulation of peripheral B cells.

Author information

1
Department of Immunology, University of Birmingham Medical School, UK. macleicm@novell2.bham.ac.uk

Abstract

Recent studies indicate that immature B cells compete with recirculating B cells for survival signals. The signals, delivered through the B-cell receptor for antigen, induce immature cells to differentiate into recirculating cells and maintain the survival of recirculating cells. They do not induce proliferation or differentiation to antibody-producing cells.

PMID:
9602312
DOI:
10.1016/s0952-7915(98)80252-5
[Indexed for MEDLINE]

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