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Epidemiol Infect. 1998 Mar;120(2):179-86.

An epidemiologic study of herpes simplex virus type 1 and 2 infection in Japan based on type-specific serological assays.

Author information

1
Infectious Diseases Surveillance Center, National Institute of Infectious Diseases, Tokyo, Japan.

Abstract

A seroepidemiologic study of herpes simplex virus type 1 (HSV-1) and 2 (HSV-2) was performed on Japanese adults. Serum samples collected between 1985-9 from a total of 536 healthy adults, female prostitutes, males with sexually transmitted diseases (STD), homosexual men, and pregnant women were studied by immunodot assays using HSV type-specific antigens, glycoproteins G (gG1 and gG2). HSV-1 infections correlated mostly with age and was widely prevalent among subjects < 40 years. HSV-2 prevalence varied greatly among subgroups defined by sexual activity and was associated with risk behaviours for prostitution, infection with STD, and homosexual activity. HSV-2 seroprevalence was highest among prostitutes (80%), lowest among pregnant women (7%), and intermediate in STD patients (23%) and homosexuals (24%). Because HSV-1 infection during childhood has been decreasing, primary genital HSV-2 infection, with its higher frequency of clinical manifestations, will become a greater burden to the public health in Japan.

PMID:
9593488
PMCID:
PMC2809388
DOI:
10.1017/s095026889700856x
[Indexed for MEDLINE]
Free PMC Article

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