Format

Send to

Choose Destination
Am Heart J. 1998 May;135(5 Pt 1):833-7.

Alcohol consumption and idiopathic dilated cardiomyopathy: a case control study.

Author information

1
Department of Clinical Cardiology, National Cardiac Centre, Mater Misericordiae Hospital, Dublin, Ireland.

Abstract

BACKGROUND:

Alcohol has been implicated as a risk factor for idiopathic dilated cardiomyopathy (DCM), but a causal relation has not been established. The objective of this study was to determine the association between alcohol consumption and DCM.

METHODS:

Questionnaires detailing average weekly intake of alcohol, total lifetime consumption, and alcohol abuse were administered in a cohort of well-defined patients with DCM and a randomly selected, population-based control group.

RESULTS:

Significantly more of the 100 patients with DCM than the 211 members of the control group drank greater than the recommended weekly intake of alcohol (40% vs 24%; p < 0.01) and were alcohol abusers according to the CAGE questionnaire (27% vs 16%; p < 0.05). The average total lifetime consumption measured in units of alcohol was also significantly greater in cases than in the control group (31,200 vs 7,904; p < 0.01). Patients with familial DCM were not significantly more likely to consume alcohol above recommended limits or to be alcohol abusers compared with nonfamilial cases.

CONCLUSIONS:

This study confirms previous suspicion of a causal association between alcohol and DCM, with significantly more patients than members of the control group either abusing alcohol or drinking it in excess of recommended limits.

PMID:
9588413
DOI:
10.1016/s0002-8703(98)70042-0
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center