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J Pediatr. 1998 Apr;132(4):731-4.

The effect of inhaled nitric oxide therapy on bleeding time and platelet aggregation in neonates.

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1
Department of Pediatrics, University of Iowa College of Medicine, Iowa City, USA.

Abstract

The effect of inhaled nitric oxide (iNO) on bleeding time and platelet aggregation was studied in nine newborn infants with resolving pulmonary hypertension. Infants treated with iNO at 40 ppm for 30 minutes had bleeding times that were nearly twofold longer than those obtained 24 hours after iNO was discontinued. iNO had no effect on in vitro platelet aggregation studies.

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PMID:
9580780
[Indexed for MEDLINE]

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