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Chem Biol. 1998 May;5(5):R97-103.

Caspases: key mediators of apoptosis.

Author information

1
Merck Research Laboratories, Rahway, NJ 07065, USA. nancy_thornberry@merck.com

Abstract

Recent studies have established that members of the caspase protease family are essential components of a conserved cell death program. Insights into their biological roles, structure and mechanism are enabling investigators to begin to explore the therapeutic potential of caspase inhibition.

PMID:
9578633
DOI:
10.1016/s1074-5521(98)90615-9
[Indexed for MEDLINE]
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