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Chem Biol. 1998 May;5(5):R97-103.

Caspases: key mediators of apoptosis.

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1
Merck Research Laboratories, Rahway, NJ 07065, USA. nancy_thornberry@merck.com

Abstract

Recent studies have established that members of the caspase protease family are essential components of a conserved cell death program. Insights into their biological roles, structure and mechanism are enabling investigators to begin to explore the therapeutic potential of caspase inhibition.

PMID:
9578633
[Indexed for MEDLINE]
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