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Lett Appl Microbiol. 1998 Mar;26(3):224-6.

The content of prostaglandins and their precursors in Mortierella and Cunninghamella species.

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Department of Biochemical Technology, Chemical Faculty, Slovak Technical University, Bratislava, Slovak Republic.


Five strains of filamentous fungi belonging to the genera Mortierella and Cunninghamella were examined for the content of dihomo-gamma-linolenic, arachidonic, eicosapentaenoic acids and prostaglandins (type E2 and F2 alpha). Prostaglandins were detected using an ELISA method in mycelia of all tested strains (range 50-4800 ng g-1 of PGE2 and 6-30 ng g-1 of PGF2 alpha). Several micro-organisms also produced prostaglandins in the culture medium (2.2-137.6 micrograms 1-1 for PGE2 and 0.4-7.8 micrograms 1-1 for PGF2 alpha).

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