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Curr Opin Neurobiol. 1998 Feb;8(1):149-56.

Genetic analysis of synaptic development and plasticity: homeostatic regulation of synaptic efficacy.

Author information

1
Howard Hughes Medical Institute, Department of Molecular and Cell Biology, University of California, Berkeley 94720, USA. gdavis@coreys.berkeley.edu

Abstract

When experimentally challenged with perturbations in synaptic structure and function, neurons have the remarkable ability to regulate their synaptic efficacy back to the normal range. Recent genetic analysis has provided insights into the mechanisms controlling this form of synaptic homeostasis, with implications for our understanding of synaptic development and plasticity.

PMID:
9568402
DOI:
10.1016/s0959-4388(98)80018-4
[Indexed for MEDLINE]

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