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Curr Opin Neurobiol. 1998 Feb;8(1):18-26.

Patterning of the embryonic forebrain.

Author information

1
Nina Ireland Laboratory of Developmental Neurobiology, Department of Psychiatry, University of California, San Francisco 94143-0984, USA. jlrr@cgl.ucsf.edu

Abstract

The vertebrate forebrain is derived from the anterior neural plate, where anteroposterior, dorsoventral and local patterning mechanisms specify regional identify. The recent identification of genetic regulators of these processes has opened the way to elucidating how the major forebrain regions (i.e. cerebral cortex, basal ganglia, thalamus, and hypothalamus) are formed, and how molecular lesions in these processes cause human birth defects.

PMID:
9568388
DOI:
10.1016/s0959-4388(98)80004-4
[Indexed for MEDLINE]

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