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Psychophysiology. 1998 May;35(3):283-92.

Magnetoencephalographic recordings demonstrate attentional modulation of mismatch-related neural activity in human auditory cortex.

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Research Imaging Center, University of Texas Health Science Center, San Antonio 78240-6240, USA.


It is widely agreed that the negative brain potential elicited at 150-200 ms by a deviant, less intense sound in a repetitive series can be modulated by attention. To investigate whether this modulation represents a genuine attention effect on the mismatch negativity (MMN) arising from auditory cortex or attention-related activity from another brain region, we recorded both the MMN and the mismatch magnetic field (MMF) elicited by such deviants in a dichotic listening task. Deviant tones in the attended ear elicited a sizable MMF that was well modeled as a dipolar source in auditory cortex. Both the MMN and MMF to unattended-ear deviants were highly attenuated. These findings support the view that the MMN/MMF elicited in auditory cortex by intensity deviants, and thus the underlying feature-analysis and mismatch-detection processes, are not strongly automatic but rather can be gated or suppressed if attention is strongly focused elsewhere.

[Indexed for MEDLINE]

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