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J Clin Gastroenterol. 1998 Mar;26(2):117-20.

Autoimmune (Hashimoto's) thyroiditis associated with Crohn's disease.

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Division of Gastroenterology, Brown University School of Medicine, Providence, Rhode Island, USA.


We report the occurrence of autoimmune (Hashimoto's) thyroiditis in three patients with Crohn's disease. Previously, thyroid disease has been described only in association with ulcerative colitis. We review the pertinent literature on thyroid disease in inflammatory bowel disease (IBD) and suggest that this association supports the hypothesis that autoimmunity is involved in the pathogenesis of IBD. Early diagnosis and treatment of thyroid dysfunction in patients with IBD is desirable because thyroid dysfunction worsens the symptoms and course of IBD.

[Indexed for MEDLINE]

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