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Curr Biol. 1998 Apr 23;8(9):R313-6.

G-protein signaling: fine-tuning signaling kinetics.

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1
Howard Hughes Medical Institute, Department of Physiology, University of California San Francisco, California 94143, USA. zerangue@phy.ucsf.edu

Abstract

Mammalian 'regulators of G protein signaling' (RGS proteins) help shut off G-protein-mediated signaling by GTPase activation. But new evidence shows that RGS proteins can also speed up the activation of signaling. The combined effect is a change in signaling kinetics without a decrease in signaling intensity.

PMID:
9560334
[Indexed for MEDLINE]
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