Format

Send to

Choose Destination
See comment in PubMed Commons below
BMJ. 1998 Apr 11;316(7138):1122-6.

Open randomised study of use of levonorgestrel releasing intrauterine system as alternative to hysterectomy.

Abstract

OBJECTIVES:

To assess whether the levonorgestrel intrauterine system could provide a conservative alternative to hysterectomy in the treatment of excessive uterine bleeding.

DESIGN:

Open randomised multicentre study with two parallel groups: a levonorgestrel intrauterine system group and a control group.

SETTING:

Gynaecology departments of three hospitals in Finland.

SUBJECTS:

Fifty six women aged 33-49 years scheduled to undergo hysterectomy for treatment of excessive uterine bleeding.

INTERVENTIONS:

Women were randomised either to continue with their current medical treatment or to have a levonorgestrel intrauterine system inserted.

MAIN OUTCOME MEASURE:

Proportion of women cancelling their decision to undergo hysterectomy.

RESULTS:

At 6 months, 64.3% (95% confidence interval 44.1 to 81.4%) of the women in the levonorgestrel intrauterine system group and 14.3% (4.0 to 32.7%) in the control group had cancelled their decision to undergo hysterectomy (P < 0.001).

CONCLUSIONS:

The use of the levonorgestrel intrauterine system is a good conservative alternative to hysterectomy in the treatment of menorrhagia and should be considered before hysterectomy or other invasive treatments.

PMID:
9552948
PMCID:
PMC28513
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Support Center