Format

Send to

Choose Destination
Trends Biochem Sci. 1998 Feb;23(2):63-7.

An atlas of serpin conformations.

Author information

1
Department of Haematology, University of Cambridge, MRC Centre, UK.

Abstract

The serpins are a family of proteins that inhibit chymotrypsin-like serine proteinases, with an unusual mechanism involving a large conformational change known as the stressed-->relaxed (S-->R) transition. This article is a guide to the known serpin conformations and their biological significance.

PMID:
9538691
DOI:
10.1016/s0968-0004(97)01172-9
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center