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Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract.

Wellington CL, Ellerby LM, Hackam AS, Margolis RL, Trifiro MA, Singaraja R, McCutcheon K, Salvesen GS, Propp SS, Bromm M, Rowland KJ, Zhang T, Rasper D, Roy S, Thornberry N, Pinsky L, Kakizuka A, Ross CA, Nicholson DW, Bredesen DE, Hayden MR.

J Biol Chem. 1998 Apr 10;273(15):9158-67.


Casper is a FADD- and caspase-related inducer of apoptosis.

Shu HB, Halpin DR, Goeddel DV.

Immunity. 1997 Jun;6(6):751-63.


D4-GDI, a substrate of CPP32, is proteolyzed during Fas-induced apoptosis.

Na S, Chuang TH, Cunningham A, Turi TG, Hanke JH, Bokoch GM, Danley DE.

J Biol Chem. 1996 May 10;271(19):11209-13.

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