Format

Send to

Choose Destination
Biochim Biophys Acta. 1998 Feb 2;1369(1):1-6.

Molecular cloning and functional expression of a rabbit renal organic cation transporter.

Author information

1
Department of Biopharmaceutical Sciences, University of California, San Francisco 94143, USA.

Abstract

A cDNA encoding an organic cation transporter (rbOCT1) was isolated from rabbit kidney. The cDNA encodes a 554 amino acid protein that is highly homologous to other mammalian organic cation transporters. rbOCT1 mediated 3H-1-methyl-4-phenylpyridinium (3H-MPP+) transport in Xenopus laevis oocytes was saturable, sensitive to membrane potential, and inhibited by various organic cations. rbOCT1 mRNA transcripts are expressed in the kidney, liver, and intestine.

PMID:
9528667
DOI:
10.1016/s0005-2736(97)00207-1
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center