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Unfallchirurg. 1998 Jan;101(1):42-9.

[Prospective randomized pilot study of ambulatory prevention of thromboembolism. 2 times 500 mg aspirin (ASS) vs. clivarin 1750 (NMH)].

[Article in German]

Author information

1
Klinik für Unfallchirurgie, Philipps-Universität Marburg.

Abstract

From March 1994 to March 1996, 287 patients, presenting with lower extremity injuries, who required immobilizing bandages or casts, where included in a prospective, randomized study. These patients received either low-molecular heparin or acetylsalicylic acid for thrombosis prophylaxis. In all patients a clinical examination and a colour-coded duplex sonography were performed after removal of the cast for detection of lower extremity venous thrombosis. A plebography was performed when thrombosis was suspected. A subcutaneous injection of divarin 1750 was given once daily in 143 patients. Thrombosis prophylaxis with Aspirin 2 x 500 mg administered orally was performed in 144 patients. Deep vein thrombosis occurred in 9 patients (6.3%) with clivarin prophylaxis and in 7 patients (4.8%) treated with Aspirin. In both groups, no clinically significant side effects of the medications were observed.

PMID:
9522671
DOI:
10.1007/s001130050231
[Indexed for MEDLINE]

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