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Am J Gastroenterol. 1998 Mar;93(3):360-2.

Bilirubinate granules: main pathologic bile component in patients with idiopathic acute pancreatitis.

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1
Department of Internal Medicine, La Paz Hospital, Autonoma University, Madrid, Spain.

Abstract

OBJECTIVE:

The aim of this study was to evaluate the main pathologic component of bile obtained by biliary drainage in patients with acute idiopathic pancreatitis and therapeutic implications.

METHOD:

Eighteen patients diagnosed with idiopathic acute pancreatitis underwent biliary drainage. Microscopic evaluation of bile was performed and pathologic components were classified in cholesterol microcrystals, bilirubinate granules, and calcium microspherolites.

RESULTS:

Five patients showed no abnormalities. In 11 patients, bilirubinate granules were found, cholesterol microcrystals in two, and Giardia lamblia in two.

CONCLUSION:

Bilirubinate granules are the main pathologic component of bile in patients with acute idiopathic pancreatitis. Cholecystectomy is the preferred therapeutic approach.

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