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Anal Biochem. 1998 Mar 15;257(2):112-9.

Development of a scintillation proximity assay for peroxisome proliferator-activated receptor gamma ligand binding domain.

Author information

1
Department of Molecular Biochemistry, Glaxo Wellcome, Inc., Research Triangle Park, North Carolina 27709-3398, USA.

Erratum in

  • Anal Biochem 1998 Oct 1;263(1):126.

Abstract

A scintillation proximity assay for peroxisome proliferator-activated receptor gamma ligand binding domain is described. Scintillation proximity offers an equilibrium method for detecting ligands that is both cost effective and fully automatable. The method described here is the first reported scintillation proximity assay for a peroxisome proliferator-activated receptor. The design of this system is generic in nature, allowing it to be adapted for other ligand binding proteins.

PMID:
9514791
DOI:
10.1006/abio.1997.2557
[Indexed for MEDLINE]

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