Abstract
During 1995, among 1105 HIV patients explored in our department, 64 presented a deep fungic infection (5.8%). The yeast was searched for in cerebrospinal fluid, blood, urine, and bronchoalveolar aspiration. Isolated germs were Cryptococcus neoformans (95%), Candida tropicalis (1 case), Saccharomyces cerevisiae (1 case) et Aspergillus fumigatus (1 case). Results of treatment with amphotericin B were: recovery (9%), clinical success (11%), out of sight (14%), letality (66%), relapse (23%) and side effects (19%). We emphasized diagnostical and therapeutical difficulties, and bad prognostic of mycoses in patients with AIDS.
MeSH terms
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Acquired Immunodeficiency Syndrome / complications*
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Amphotericin B / therapeutic use
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Antifungal Agents / therapeutic use
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Aspergillosis / complications
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Aspergillosis / drug therapy
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Aspergillosis / microbiology
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Aspergillus fumigatus / isolation & purification
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Body Fluids / microbiology
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Candida / isolation & purification
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Candidiasis / complications
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Candidiasis / drug therapy
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Candidiasis / microbiology
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Cote d'Ivoire
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Cryptococcosis / complications
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Cryptococcosis / drug therapy
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Cryptococcosis / microbiology
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Cryptococcus neoformans / isolation & purification
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Humans
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Mycoses / complications*
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Mycoses / drug therapy
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Mycoses / microbiology
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Prognosis
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Saccharomyces cerevisiae / isolation & purification
Substances
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Antifungal Agents
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Amphotericin B