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Trends Microbiol. 1998 Feb;6(2):61-5.

The clinical significance of T-cell superantigens.

Author information

1
Dept of Paediatrics, Ealing Hospital NHS Trust, Middlesex, UK. colinm@easynet.co.uk

Abstract

Superantigens are a diverse collection of molecules that share the ability to activate specific lymphocyte subsets. In animal models, many of these molecules delete T-cell populations or render them anergic. The clinical impact of superantigens is significant, but much of their pathophysiology remains unclear.

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PMID:
9507640
DOI:
10.1016/S0966-842X(97)01193-1
[Indexed for MEDLINE]

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