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Curr Opin Immunol. 1997 Dec;9(6):851-7.

Mediators of inflammation.

Author information

1
Department of Epidemiology, Yale University School of Medicine, New Haven, CT 06520-8034, USA.

Abstract

Therapeutic studies and genetically engineered animals have elucidated the inflammatory roles of cytokines and chemokines in autoimmune disease. Most unexpected has been a continuum of recent evidence demonstrating that inflammatory mediators are crucial in lymphoid organ development, thus suggesting that these hitherto unrelated processes have common elements with implications for determinant spreading.

PMID:
9492989
[Indexed for MEDLINE]

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