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Thyroid. 1998 Jan;8(1):107-13.

Autonomy in endemic goiter.

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  • 1Institute of Interdisciplinary Research, School of Medicine, University of Brussels, Belgium.

Abstract

The occurrence of hyperthyroidism in many individuals after introduction of iodine prophylaxis in endemic goiter areas can have dramatic consequences for the affected individuals. It indicates that in such individuals the increase of serum thyroid hormone level in response to iodine supplementation does not exert its normal negative feedback on thyroid activity, ie, that in such individuals some thyroid tissue has become autonomous. In this short review we summarize what is known about the possible mechanisms, cause, diagnosis, and consequences of thyroid autonomy.

PMID:
9492160
DOI:
10.1089/thy.1998.8.107
[PubMed - indexed for MEDLINE]
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