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J Am Acad Dermatol. 1998 Feb;38(2 Pt 2):318-21.

Super potent topical corticosteroid use associated with adrenal suppression: clinical considerations.

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  • 1Department of Medicine, UCSD School of Medicine, San Diego, California, USA.


The potential for a variety of local and systemic side effects from the use of potent topical corticosteroids has long been recognized. However, adrenal suppression has only rarely been documented. We describe two patients with profound hypothalamic-pituitary-adrenal axis suppression resulting from the unregulated use of super potent topical corticosteroids.

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