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Curr Opin Genet Dev. 1997 Dec;7(6):835-40.

Insights into the evolutionary process from patterns of DNA sequence variability.

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Cornell University, Section of Genetics and Development, Ithaca, New York 14853, USA. CFA1@CORNELL.EDU


Studies of DNA sequence diversity, particularly in Drosophila, reveal both the complexity of natural selection and the importance of the interaction of natural selection and variation in rates of recombination within genomes and between species in determining levels of sequence variability in different genes and different species. The impact of both adaptive and deleterious mutations are evident. Extension of these types of studies to other organisms has begun in earnest.

[Indexed for MEDLINE]

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