Format

Send to

Choose Destination
Eur J Vasc Endovasc Surg. 1997 Dec;14(6):439-45.

Lipid-rich carotid artery plaques appear echolucent on ultrasound B-mode images and may be associated with intraplaque haemorrhage.

Author information

1
Department of Vascular Surgery, University Hospital of Copenhagen, Rigshospitalet, Denmark.

Abstract

OBJECTIVE:

To relate the histological composition of carotid artery plaques with morphology as evaluated by B-mode ultrasound.

DESIGN:

Prospective study.

MATERIAL AND METHODS:

Seventy-eight symptomatic patients underwent carotid endarterectomy after preoperative ultrasound Duplex scanning evaluating plaque morphology. Morphometric analysis of the removed specimen was performed in order to quantify content of lipid, haemorrhage, calcification and fibrous tissue.

RESULTS:

Echolucent plaques contained more lipid (p = 0.01) and less calcification (p = 0.01) and fibrous tissue (p = 0.03) than echo-rich plaques. Intraplaque haemorrhage was directly related to lipid content (p = 0.004) and inversely related to amount of fibrous tissue in the plaque (p = 0.02).

CONCLUSION:

The intensity of the reflected B-mode ultrasound signal appears related to the histological composition of the plaque. The association between intraplaque haemorrhage and a high lipid content may support the theory of the lipid-rich plaque being more prone to rupture.

PMID:
9467517
DOI:
10.1016/s1078-5884(97)80121-9
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center