Format

Send to

Choose Destination
J Chromatogr B Biomed Sci Appl. 1997 Nov 21;702(1-2):211-5.

Quantitative analysis by gas chromatography of volatile carbonyl compounds in expired air from mice and human.

Author information

1
Department of Viticulture and Enology, University of California, Davis 95616, USA.

Abstract

Formaldehyde, acetaldehyde and acetone expired from tumor-bearing transgenic mice and formaldehyde exhaled from breast cancer patients were analyzed using gas chromatography. The tumor-bearing mice expired significantly more formaldehyde per unit metabolic size (1.43-2.98 micromol) than did control mice (0.77-1.01 micromol). There was no detectable difference in the levels of expired acetaldehyde and acetone between the two groups of mice. The exhaled formaldehyde levels from three women with breast cancer and from three healthy women were satisfactorily determined using the method developed in this study. The results suggest that these carbonyl compounds may be used as a biomarker.

PMID:
9449573
DOI:
10.1016/s0378-4347(97)00369-1
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center