DNA sequence variation within vanA, vanB, vanC-1, and vanC-2/3 genes of clinical Enterococcus isolates

Antimicrob Agents Chemother. 1998 Jan;42(1):202-5. doi: 10.1128/AAC.42.1.202.

Abstract

We studied the DNA sequence variation of van genes of 34 isolates of Enterococcus spp. The isolates containing the vanB gene exhibited between 0 and 41 base pair changes per 801 bp studied when the vanB sequences were compared to that of the reference strain Enterococcus faecalis V583. The isolates carrying the vanC-2 gene exhibited between 0 and 23 base pair changes per 346 bp studied when the vanC-2 sequences were compared to that of the reference strain E. casseliflavus ATCC 25788. Little variation was noted in the vanA and vanC-1 genes.

MeSH terms

  • Amino Acid Sequence
  • Bacterial Proteins / genetics*
  • Base Sequence
  • Carbon-Oxygen Ligases / genetics*
  • Enterococcus / genetics*
  • Genetic Variation
  • Humans
  • Molecular Sequence Data
  • Peptide Synthases / genetics*
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Sequence Homology, Amino Acid
  • Sequence Homology, Nucleic Acid

Substances

  • Bacterial Proteins
  • VanA ligase, Bacteria
  • VanB protein, Enterococcus
  • VanC protein, Bacteria
  • Carbon-Oxygen Ligases
  • Peptide Synthases
  • VanC protein, Enterococcus

Associated data

  • GENBANK/L29639
  • GENBANK/U72704
  • GENBANK/U72705
  • GENBANK/U72706
  • GENBANK/U94521
  • GENBANK/U94522
  • GENBANK/U94523
  • GENBANK/U94524
  • GENBANK/U94525
  • GENBANK/U94526
  • GENBANK/U94528