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Pediatr Dermatol. 1997 Nov-Dec;14(6):477-9.

Ear lobe bilateral necrosis by levamisole-induced occlusive vasculitis in a pediatric patient.

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1
Istituto di Scienze Dermatologiche, Clinica pediatrica II, Università degli Studi di Milano, Milan, Italy.

Abstract

We describe a bullous-hemorrhagic reaction of the ear lobes in a child with nephrosis after levamisole intake. This drug is used in children as an alternative treatment of corticosteroid-responsive nephrotic syndrome. Histologic evaluation of a lesion revealed necrotizing vasculitis involving mainly the large vessels of the deep plexus. The lesions disappeared 25 days after discontinuation of treatment.

PMID:
9436850
[Indexed for MEDLINE]
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