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Biochim Biophys Acta. 1997 Dec 5;1343(2):187-92.

Protein-protein interaction between the RVS161 and RVS167 gene products of Saccharomyces cerevisiae.

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Laboratoire de Biologie Cellulaire des Levures, IBGC-CNRS, Bordeaux, France.


As previous studies indicated that the RVS161 and RVS167 gene products of Saccharomyces cerevisiae seem to be involved in the same cellular function, we considered the possibility of a complex between the proteins encoded by these two genes. Using the two hybrid system, we have shown that Rvs167p interacts with Rvs161p, through its N-terminal domain which contains predicted coiled-coil structures. Moreover, if a tagged Rvs 167p protein was immuno adsorbed under non-denaturing conditions, it brought along the Rvs161p protein. These results confirmed the hypothesis of an in vivo complex between the two proteins.

[Indexed for MEDLINE]

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