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Pediatr Radiol. 1998 Jan;28(1):23-9.

Post-infectious bronchiolitis obliterans: clinical, radiological and pulmonary function sequelae.

Author information

1
Mater Misericordiae Children's Hospital, South Brisbane, Queensland 4101, Australia.

Abstract

BACKGROUND:

There are few data on clinical, chest radiograph (CXR) or pulmonary function sequelae in children with post-infectious bronchiolitis obliterans (BO) (pulmonary crepitations, abnormalities on CXR, CT, nuclear medicine scans, or bronchography, with a history of past pulmonary infection and in the absence of other underlying pathology).

OBJECTIVE:

To analyse the methodology of diagnosis, long-term clinical imaging and pulmonary function sequelae of post-infectious BO in children.

MATERIALS AND METHODS:

Imaging (CXRs, CT and nuclear lung scans) and clinical histories of 19 children were analysed.

RESULTS:

Clinical follow-up (mean 6.8 years), revealed a high incidence of continuing problems (asthma and bronchiectasis). Fixed airway obstruction was the most common pulmonary function sequela. The sequelae on follow-up (mean 5.8 years) CXR were classified into five patterns which are illustrated: unilateral hyperlucency of an enlarged lung/part of lung; complete collapse of the affected lobe; unilateral hyperlucency of a small or normal-sized lung; bilateral hyperlucent lungs and a mixed pattern of persistent collapse, hyperlucency and peribronchial thickening.

CONCLUSION:

Long-term observations in children with post-infectious BO should be undertaken to detect bronchiectasis and obstructive airway disease. Sequelae evident on CXR, other than those previously described, can be found. Bronchography and/or lung biopsy are not usually required for the diagnosis of post-infectious BO.

PMID:
9426269
DOI:
10.1007/s002470050286
[Indexed for MEDLINE]

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