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Curr Opin Biotechnol. 1997 Dec;8(6):718-23.

Post-translational modification of proteins and the discovery of new medicine.

Author information

1
Oxford GlycoSciences (UK) Ltd., Abingdon, UK. chrohlff@ogs.co.uk

Abstract

Post-translational modifications are fundamental to processes controlling behaviour, including cellular signaling, growth and transformation. As the molecular basis of protein modifications in normal and disease processes are becoming better defined, so new strategies for designing therapeutic entities to control complex disease processes are emerging.

PMID:
9425663
DOI:
10.1016/s0958-1669(97)80126-7
[Indexed for MEDLINE]

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