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Int J Gynecol Pathol. 1997 Oct;16(4):383-6.

Fibromatosis of soft tissue type involving the female genital tract: a report of two cases.

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James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA.


Two cases of soft tissue-type fibromatosis of the female genital tract are described. One involved the vulva of a 19-year-old woman, and was approximately 6.0 cm in greatest dimension and had a rubbery consistency with a gray-white, whorled cut surface. Microscopically, it had infiltrating borders and extended to the ischio-rectal region. All gross tumor was resected. There was no evidence of recurrent disease 6 years later. The other tumor involved primarily the ovary of a 20-year-old woman. It was 24 cm in greatest dimension and infiltrated the mesentery, psoas muscle, and iliac vessels. The tumor was resected along with the sigmoid colon and the patient was free of disease 3 months later. Fibromatosis of the female genital tract, histologically identical to the soft tissue lesion and distinct from so-called "ovarian fibromatosis," should be included in the differential diagnosis of low-grade spindle cell lesions of this region.

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