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Pac Symp Biocomput. 1997:477-85.

TRANSFAC database as a bridge between sequence data libraries and biological function.

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Gesellschaft für Biotechnologische Forschung mbH, Braunschweig.


The TRANSFAC database contains information about regulatory DNA sequences and the proteins (transcription factors) binding to and acting through them. It may thus serve as a dictionary for the biological meaning of these sequence elements. Moreover, the TRANSFAC data can be used to describe these elements, to define consensi and matrices for elements of certain function, and thus to provide means of identifying regulatory signals in newly unravelled genomic sequences.

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