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Chem Biol. 1995 Jan;2(1):7-12.

Strategies for the design of minor groove binders: a re-evaluation based on the emergence of site-selective carbohydrate binders.

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1
Department of Chemistry, Princeton University, NJ 08544-1009, USA.

Abstract

Studies on minor groove binders provide new insights into DNA structure and recognition, information that may in the future serve as the basis for the design of synthetic binders targeted to particular minor groove sites. Carbohydrate-based minor groove binders are emerging as a particularly interesting and important class of ligands for DNA.

PMID:
9383398
[Indexed for MEDLINE]
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